From single-cell electroporation to multi-electrode biomedical protocols — EPULSUS generators deliver the waveform control that life sciences research demands.
Biological applications of pulsed electric fields require a level of waveform precision that generic high-voltage sources cannot provide. Pulse width, rise time, polarity, burst frequency and inter-pulse interval all influence cellular response — and must be independently controlled, reproducible and well-characterised.
EPULSUS generators are developed in close collaboration with research groups working in electroporation, bioelectrics and cell biology. Every parameter is software-controllable, logged and exportable. Results are reproducible across experiments and across laboratories.
The BM1A-12 extends this capability to laboratory-scale food science and agri-food research — providing the same waveform rigour in a complete bench-top PEF system with integrated treatment chambers.
Used by
Molecular biologists
Biomedical engineers
Electroporation researchers
Gene therapy labs
Neuroscience groups
Food science researchers
Agricultural research institutes
Biotech companies
University research groups
Applications
What researchers use EPULSUS generators for
Regulatory status shown refers to the clinical technique, not to EPS equipment. EPS supplies generators for research and development; they are not medical devices and carry no clinical approvals.
Research
Electroporation & Gene Transfer
Reversible permeabilisation of cell membranes for controlled delivery of drugs, DNA, RNA, proteins and small molecules. Used widely in molecular biology, gene therapy research, CRISPR delivery and transfection protocols. Bipolar pulse control optimises uptake while preserving cell viability.
EPS research platforms: FBML1-5 · FPM4-10
Oncology · Clinically established
Irreversible Electroporation (IRE)
Non-thermal tumour ablation in clinical use for liver, pancreas and prostate cancers. Preserves blood vessels, bile ducts and other critical structures within the ablation zone — a research field EPS generators support.
EPS research platforms: FBML1-5 · FPM4-10
Oncology · Established clinical technique
Electrochemotherapy (ECT)
Combination of electroporation with cytotoxic drugs (bleomycin or cisplatin) to treat cutaneous and subcutaneous tumours. ESOPE protocol established in 2006 with reported objective response rates of around 85%. In routine clinical use for skin metastases across European cancer centres.
EPS research platforms: FPM4-10
Investigational
Calcium Electroporation
Emerging anti-cancer technique using electroporation to introduce supraphysiological calcium concentrations into tumour cells, inducing ATP depletion and selective cell death. Phase II clinical trials in cutaneous metastases, recurrent head & neck cancer and colorectal cancer — research EPS generators enable.
EPS research platforms: FBML1-5 · FPM4-10
Cardiology · Clinically established
Pulsed Field Ablation (PFA)
Non-thermal cardiac tissue ablation for atrial fibrillation. More tissue-selective than thermal alternatives — a fast-growing area where EPS supports waveform research.
EPS research platforms: FBML1-5 · FPM4-10
Research
Cell Stimulation & Waveform Research
Sub-microsecond stimulation for neuroscience, cardiac electrophysiology and fundamental bioelectrics research. Nanosecond pulsed electric fields (nsPEF) for intracellular targeting. Full waveform programmability across independent channels — voltage, pulse width, burst count, polarity and timing.
EPS research platforms: FBML1-5 · FPM4-10
Research
Food Science & Agri-Food Research
Laboratory and pilot-scale PEF studies for polyphenol extraction, microbial inactivation, cell permeabilisation in plant tissue and juice processing. Complete bench-top system with interchangeable batch and continuous treatment chambers. Published results transferable to industrial scale.
EPS research platforms: BM1A-12
Custom
Custom & Emerging Research
New applications of pulsed electric fields in biology continue to emerge. EPS works directly with research groups to adapt generator parameters, develop application-specific protocols and co-publish results. Contact us to discuss your specific requirements.
Solid-state Marx topology, Si IGBT and SiC MOSFET switching, bipolar multilevel waveform generation, rise time physics and application notes — all in our Technology section.
